Month: January 2026

Nathaniel Jorgenson Polar surface area (PSA) is a widely used molecular descriptor in pharmaceutical research, closely linked to properties such as permeability, solubility, and oral absorption. In practice, PSA is most often estimated computationally from molecular structure, providing a convenient…

A CRO’s perspective on faster, more informative antibody analytics and processes… Matthew Crawford As a CRO supporting biologics developers from early discovery through late-stage manufacturing, we’re constantly asked the question: How can we get reliable antibody data faster, with less…

Nathaniel Jorgenson In liquid chromatography, mobile phase modifiers play a critical role in controlling analyte retention and peak shape. Mobile phase modifiers are small quantities of acids or bases added to chromatographic solvents to fine-tune the chemical environment of the…