Library Purifications

The Rilas Platform for library purification has been fine tuned to purify each compound with the highest purity achievable in the most efficient way possible. We work with our customers to ensure seamless integration of their compounds into our processes and return the purified samples in a format which makes them easy to submit for biological screening and storage, or any other downstream processes required. Purified libraries have a more homogenous character, allowing for the downstream analytics teams to inform upstream with much more confidence than with crude libraries.

As part of The Rilas Platform, we also have a wide range of analytical options for customers to choose from to screen their libraries’ post purification. These include:

LCMS QC - Rapid molecular weight and purity confirmation
EPSA Measurements - Analysis to determine the experimental polar surface area
Covalent Binder Analysis - Screening and characterization of irreversible binders
Solubility & Stability - Assessment of solubility and stability across various media and stress conditions
Biomimetic Chromatography - Simulate ADME characteristics without the need for expensive, time-consuming biological assays