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Sequence Confirmation of Oligonucleotides through Collision Induced Dissociation Tandem Mass Spectrometry

July 26, 2024

Matthew Crawford, MS In the realm of molecular biology, the elucidation of DNA and RNA sequences is essential to furtheringresearch and maintaining high therapeutic quality. Oligonucleotides, short nucleic acids, play a crucialrole in various biological processes and are extensively employed…

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Navigating the Frontier of Proteomics: Intact Protein Mass Spectrometry vs. Native Protein Mass Spectrometry

June 18, 2024

Matthew Crawford, MS Proteomics, the study of proteins and their functions within organisms, has revolutionized our understanding of biological systems. Mass spectrometry (MS) plays a pivotal role in proteomic research, enabling the identification, characterization, and quantification of proteins with unparalleled…

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Understanding the Impact of Non-Volatile Salts in Mass Spectrometry Analysis

May 15, 2024

Matthew Crawford, MS Mass spectrometry (MS) has revolutionized the field of proteomics and genomics, enabling researchers tounravel the complex structures and functions of proteins and nucleic acids with unprecedented precision.However, despite its power, MS analysis can be influenced by various…

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Removing the Purification Bottleneck

May 10, 2024

Laboratory News – July, 2020

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Intact MS from a Biologist’s Perspective

April 24, 2024

Matthew Crawford, MS A question that arises frequently when discussing intact protein analysis by mass spectrometry (MS) is “why should we do mass spec analysis on intact proteins when we already have gel?” The short answer is that mass spectrometry,…

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Removing the Purification Bottleneck

March 26, 2024

Laboratory News – July, 2020

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Fragmentation-free characterization of glycopeptides with ion mobilityPOSTER PRE

March 23, 2024
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PhysChem Measurements & ReformattingCapabilities

March 19, 2024

PhysChem MeasurementsWith the expansion of our analytical HPLC capabilities, we have been able to provide our customers with high throughput compound characterizations including solubility, stability and soon logD determination. We understand the need for these rapid determinations of key physical…

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Increasing Productivity in EarlyDiscovery

March 19, 2024

Library AdvantagesThe goal of early drug discovery research is to generate biological data which requires producing a large number of synthetic compounds by medicinal chemists. One of the best ways to achieve this goal is by synthesizing different sized libraries…

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New Year, New Improvements

March 19, 2024

January 2021 Newsletter Physico-Chemical Measurements With the start of this new year, we are looking forward to expanding and improving our services and solutions for the biotech community. One of our main focuses early this year will be on providing…

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