A World-Class Chemistry Laboratory Committed to Your Needs

rilas lab

Rilas Lab™

Rilas Lab™ provides world-class purifications for clients all over the world.

Achiral Separations: Rilas uses a state-of-the-art Agilent 1290 Infinity II automated purification system that can rapidly purify samples under 500 mg in one day and purify libraries within five days.

Chiral separations: Rilas has developed an efficient and effective use of supercritical fluid chromatography (SFC) technologies resulting in pure enantiomers or diastereomers within 5 days for amounts up to 5 g.

Additional information about Rilas Lab™

  • Preparative chiral separation from milligrams up to 50 g quantities of discovery research compounds, templates, intermediates, drug candidates

  • Achiral purification and reformatting mg to gram quantities of singletons and libraries of compounds

  • Enantiomeric and diastereomeric excess confirmation of starting materials, intermediates and final products

  • Automated method development for chiral and achiral separations

  • High-throughput HPLC/MS QC of compound collections up to 1000 compounds/week

  • High-throughput solubility, stability and logD determination

  • Repeat literature analysis

  • Purity analysis by HPLC/MS

Instrumentations

  • Waters SFC Investigator

  • Waters SFC 80

  • Agilent 1290 Infinity II Mass Directed Automated Purification System

  • TECAN freedom evo 150 Liquid Handler

  • Agilent 1290 Infinity II HPLC/MS

  • Agilent 1260 HPLC/UV/ELSD

  • Genevac EZ-2

  • Buchi Rotavapors

  • Biotage V-10

We provide free pick-up and delivery within the Metro Boston area. Additional services are coming soon. Check back often.